'
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.2
USERS' SCORE
Good
Based on 3 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (as zinc picolinate)
22 mg
200%

Top Medical Research Studies

9.5
Zinc improves erectile dysfunction
Effect of oral zinc therapy on gonadal function in hemodialysis patients. A double-blind study.
Strong evidence for zinc benefits
We observed the effects of zinc on erectile dysfunction in a carefully designed study that involved a double-blind trial. Twenty stable hemodialysis patients participated, receiving either 50 mg of zinc as zinc acetate or a placebo for six months. The goal was to determine if zinc could enhance gonadal function, especially in men who often experience hormonal issues due to kidney problems.

At the end of the study, we noted significant improvements in the zinc-treated group compared to the placebo group. Those receiving zinc had a remarkable increase in plasma zinc levels, testosterone levels, and sperm counts. Specifically, testosterone levels rose from 2.8 to 5.2 ng/mL, and sperm counts doubled from 30 to 63 million/mL, indicating a marked improvement in reproductive health.

Not only did these participants show increased hormone levels, but they also experienced a noticeable drop in luteinizing hormone and follicle-stimulating hormone, suggesting improved gonadal function. Alongside these biochemical changes, many reported better potency, enhanced libido, and increased frequency of intercourse, highlighting zinc’s role in reversing some aspects of erectile dysfunction related to zinc deficiency.

In conclusion, our findings suggest that zinc deficiency can be a reversible factor contributing to erectile dysfunction in hemodialysis patients, offering hope for those struggling with this issue.
Read More
9
Zinc improves erectile dysfunction
Zinc improves sexual performance and erectile function by preventing penile oxidative injury and upregulating circulating testosterone in lead-exposed rats.
Direct evaluation of zinc's effects
We explored the impact of zinc treatment on erectile dysfunction, particularly in rats exposed to lead. The study involved twenty male Wistar rats, randomly assigned to four different groups: a control group, a group receiving zinc treatment, a group exposed to lead, and a group that received both lead and zinc therapy. This design allowed us to see how zinc could counteract the adverse effects of lead exposure on sexual function.

Our findings revealed that zinc co-administration significantly benefitted rats affected by lead, showing improvements in key sexual performance metrics. We observed enhancements in penile weight and increased latencies and frequencies of mating behaviors such as mounting, intromission, and ejaculation. In addition to these behavioral improvements, zinc treatment also helped restore important biological signals that drive sexual function, including nitric oxide and testosterone levels.

Overall, our study indicates that zinc can play a vital role in mitigating lead-induced sexual and erectile dysfunction by reducing oxidative stress and enhancing hormonal balance. This suggests potential therapeutic benefits of zinc in similar conditions affecting sexual health.
Read More
9
Zinc aids erectile function in rats
Zinc improves sexual and erectile function in HAART-treated rats via the upregulation of erectogenic enzymes and maintenance of redox balance.
Study directly addresses zinc's effects
We investigated the impact of zinc on erectile dysfunction associated with HAART (Highly Active Antiretroviral Therapy) in a controlled study involving male Wistar rats. The research included four groups: a control group, a zinc-only group, a HAART-only group, and a group treated with both HAART and zinc. Our treatment lasted for eight weeks, allowing us to observe the effects of zinc supplementation in the context of HAART-induced sexual dysfunction.

The results were quite promising. We found that zinc significantly reduced the negative impacts HAART had on key factors related to sexual performance. Specifically, zinc treatment improved latency times for mating behaviors and enhanced overall motivation to engage in sexual activity. It also increased important biochemical markers such as nitric oxide and testosterone levels while decreasing harmful enzyme activities that could contribute to erectile dysfunction.

Beyond just improving physical responses, zinc helped restore a normal balance of oxidative stress in the penis. This means that the antioxidant properties of zinc were crucial in addressing inflammation and oxidative damage caused by HAART. In essence, we learned that zinc might be a valuable addition to treatment plans for maintaining sexual health in individuals undergoing HAART.
Read More

Most Useful Reviews

9.5
Effective treatment
I found the tablets easy to take, with little smell. I took one in the morning and one at night, totalling 44mg, which is above the recommended intake, so I took them after meals to avoid stomach upset. They were effective in preventing erectile dysfunction and enhancing libido.
Read More
9.5
Important mineral
Zinc picolinate is well-absorbed and crucial for the body, improving various functions, including the reproductive system. A deficiency can lead to issues like late puberty and dysfunction of the ovaries. Zinc is particularly important for women, especially during pregnancy. Symptoms of deficiency can include fatigue and hair loss.
Read More
8.8
Supports erectile function
This zinc picolinate preparation contains 22mg per tablet. My husband took two tablets daily as directed by the doctor to support erectile function. We also use zinc for colds and viral infections, and it has proved effective in resolving symptoms quickly.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.2
9.5
Zinc improves erectile dysfunction
Effect of oral zinc therapy on gonadal function in hemodialysis patients. A double-blind study.
Strong evidence for zinc benefits
We observed the effects of zinc on erectile dysfunction in a carefully designed study that involved a double-blind trial. Twenty stable hemodialysis patients participated, receiving either 50 mg of zinc as zinc acetate or a placebo for six months. The goal was to determine if zinc could enhance gonadal function, especially in men who often experience hormonal issues due to kidney problems.

At the end of the study, we noted significant improvements in the zinc-treated group compared to the placebo group. Those receiving zinc had a remarkable increase in plasma zinc levels, testosterone levels, and sperm counts. Specifically, testosterone levels rose from 2.8 to 5.2 ng/mL, and sperm counts doubled from 30 to 63 million/mL, indicating a marked improvement in reproductive health.

Not only did these participants show increased hormone levels, but they also experienced a noticeable drop in luteinizing hormone and follicle-stimulating hormone, suggesting improved gonadal function. Alongside these biochemical changes, many reported better potency, enhanced libido, and increased frequency of intercourse, highlighting zinc’s role in reversing some aspects of erectile dysfunction related to zinc deficiency.

In conclusion, our findings suggest that zinc deficiency can be a reversible factor contributing to erectile dysfunction in hemodialysis patients, offering hope for those struggling with this issue.
Read More
9
Zinc improves erectile dysfunction
Zinc improves sexual performance and erectile function by preventing penile oxidative injury and upregulating circulating testosterone in lead-exposed rats.
Direct evaluation of zinc's effects
We explored the impact of zinc treatment on erectile dysfunction, particularly in rats exposed to lead. The study involved twenty male Wistar rats, randomly assigned to four different groups: a control group, a group receiving zinc treatment, a group exposed to lead, and a group that received both lead and zinc therapy. This design allowed us to see how zinc could counteract the adverse effects of lead exposure on sexual function.

Our findings revealed that zinc co-administration significantly benefitted rats affected by lead, showing improvements in key sexual performance metrics. We observed enhancements in penile weight and increased latencies and frequencies of mating behaviors such as mounting, intromission, and ejaculation. In addition to these behavioral improvements, zinc treatment also helped restore important biological signals that drive sexual function, including nitric oxide and testosterone levels.

Overall, our study indicates that zinc can play a vital role in mitigating lead-induced sexual and erectile dysfunction by reducing oxidative stress and enhancing hormonal balance. This suggests potential therapeutic benefits of zinc in similar conditions affecting sexual health.
Read More
9
Zinc aids erectile function in rats
Zinc improves sexual and erectile function in HAART-treated rats via the upregulation of erectogenic enzymes and maintenance of redox balance.
Study directly addresses zinc's effects
We investigated the impact of zinc on erectile dysfunction associated with HAART (Highly Active Antiretroviral Therapy) in a controlled study involving male Wistar rats. The research included four groups: a control group, a zinc-only group, a HAART-only group, and a group treated with both HAART and zinc. Our treatment lasted for eight weeks, allowing us to observe the effects of zinc supplementation in the context of HAART-induced sexual dysfunction.

The results were quite promising. We found that zinc significantly reduced the negative impacts HAART had on key factors related to sexual performance. Specifically, zinc treatment improved latency times for mating behaviors and enhanced overall motivation to engage in sexual activity. It also increased important biochemical markers such as nitric oxide and testosterone levels while decreasing harmful enzyme activities that could contribute to erectile dysfunction.

Beyond just improving physical responses, zinc helped restore a normal balance of oxidative stress in the penis. This means that the antioxidant properties of zinc were crucial in addressing inflammation and oxidative damage caused by HAART. In essence, we learned that zinc might be a valuable addition to treatment plans for maintaining sexual health in individuals undergoing HAART.
Read More
7
Zinc's variable effectiveness in CKD
Interventions for treating sexual dysfunction in patients with chronic kidney disease.
Research relevance indicates cautious optimism
We explored the role of zinc in treating erectile dysfunction, particularly in patients with chronic kidney disease (CKD). Several studies were analyzed, focusing primarily on the effectiveness of zinc compared to a placebo.

Through this review, we observed that while oral zinc treatment showed some promise in enhancing testosterone levels, particularly in one study, the overall findings were mixed. For instance, when zinc was added to dialysate, there was no significant increase in testosterone levels, which is crucial for sexual function.

The research on zinc and its effects on erectile dysfunction remains limited, and there's a clear need for more extensive studies. It's important to note that while PDE5 inhibitors, another treatment option, showed noteworthy improvements, zinc alone did not consistently deliver compelling results. This indicates that while zinc might have potential, it shouldn’t be viewed as a standalone solution for erectile dysfunction in CKD patients at this stage.
Read More
7
Zinc's mixed impact on dysfunction
Zinc, hydrochlorothiazide and sexual dysfunction.
Moderate relevance to erectile dysfunction
We conducted a study to understand how zinc might influence erectile dysfunction, particularly in men taking hydrochlorothiazide, a medication for high blood pressure. The research involved 39 middle-aged men on hydrochlorothiazide and 27 healthy men not on medication. We found a notably higher rate of sexual dysfunction among those taking hydrochlorothiazide—56% compared to just 11% in the control group.

Importantly, we noticed that hydrochlorothiazide affected serum zinc levels in some patients. In further investigation, we divided 22 men with sexual dysfunction into two groups. One received zinc supplements for a month, while the other received magnesium. After this period, we observed that zinc levels in the blood returned to normal for only eight out of the twenty-two patients, with improvements in sexual dysfunction symptoms reported by five of them.

While our findings suggest that low zinc levels might be linked to sexual dysfunction, the overall impact of zinc supplementation remains inconclusive. In fact, the improvements we saw weren't consistent across the board, and the definitive role of zinc in addressing sexual dysfunction is still up for debate.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Effective treatment
I found the tablets easy to take, with little smell. I took one in the morning and one at night, totalling 44mg, which is above the recommended intake, so I took them after meals to avoid stomach upset. They were effective in preventing erectile dysfunction and enhancing libido.
9.5
Important mineral
Zinc picolinate is well-absorbed and crucial for the body, improving various functions, including the reproductive system. A deficiency can lead to issues like late puberty and dysfunction of the ovaries. Zinc is particularly important for women, especially during pregnancy. Symptoms of deficiency can include fatigue and hair loss.
Read More
8.8
Supports erectile function
This zinc picolinate preparation contains 22mg per tablet. My husband took two tablets daily as directed by the doctor to support erectile function. We also use zinc for colds and viral infections, and it has proved effective in resolving symptoms quickly.
image